The anti-CD3 monoclonal antibody (OKT3) recognizes CD3, a human glycoprotein and member of the Ig superfamily—primarily expressed on T cells, some NKT cells, and thymocytes during T-cell differentiation. Binding of an anti-CD3 monoclonal antibody to CD3 stimulates T-cell activation. Anti-CD3 antibodies (the OKT3 clone in particular) are used toexpand T cells in culturefor use inadoptive immunotherapy. CD8+ T-cell expansion can be further enhanced by costimulation withRetroNectin reagent.
The anti-CD3 monoclonal antibody (OKT3) recognizes CD3, a human glycoprotein and member of the Ig superfamily—primarily expressed on T cells, some NKT cells, and thymocytes during T-cell differentiation. Binding of an anti-CD3 monoclonal antibody to CD3 stimulates T-cell activation. Anti-CD3 antibodies (the OKT3 clone in particular) are used to expand T cells in culture for use in adoptive immunotherapy. CD8+ T-cell expansion can be further enhanced by costimulation with RetroNectin reagent.
This product is manufactured as a quality-assured product according to relevant guidelines for Good Manufacturing Practice (GMP), and is, therefore, suitable for ex vivo cell culture processing and gene therapy studies.
