High-quality Tet System Approved FBS for cell culture has been functionally tested* to ensure that it permits the full range of tetracycline-regulated induction with well-characterized Tet cell lines. As the exclusive licensed distributor of tetracycline-controlled gene expression systems, only Takara Bio USA is certified to offer FBS that can ensure optimum induction with all tetracycline-inducible gene expression systems. Other commercial cell-culture serum products may contain tetracycline-derived contaminants which can dramatically affect the inducible regulation of Tet systems.

Because our Tet-On and Tet-Off systems are extremely sensitive, even “antibiotic-free” fetal bovine serum that has no negative effect on cell growth may still exhibit enough activity to alter Tet-regulated gene expression. You can be confident that Tet System Approved FBS will not adversely affect Tet-On or Tet-Off experiments.

*Testing for the presence of tetracyclines in fetal or calf serum is not equivalent to the highly sensitive functional testing that is performed on our Tet System Approved FBS.