Advantage Genomic LA Polymerase Mix and Advantage GC Genomic LA Polymerase Mix are designed for long and accurate (LA) PCR amplification. These mixes offer 6.5X higher fidelity than wild-type Taq DNA polymerase, and allow synthesis of products up to 30 kb for complex templates such as genomic DNA, and up to 48 kb for less complex templates such as λ DNA. Both versions of Advantage Genomic LA Polymerase Mix are composed of a full-length Taq DNA polymerase, a small amount of proofreading enzyme, and a hot-start antibody, and are supplied with optimized buffers.

The Advantage GC Genomic LA Polymerase Mix includes a 2X Advantage GC-Melt buffer to allow efficient amplification of GC-rich templates, which have strong secondary structures that resist denaturation and prevent efficient primer annealing. This kit can handle GC-rich sequences (up to 90% GC) that resist standard PCR amplification techniques, and enables synthesis of PCR products up to 20 kb from GC-rich human genomic DNA.

If you are interested in Commercial Use of our products, including OEM, bulk purchasing, or custom formulation (e.g., highly concentrated reagents, custom volumes), please contact Business Development at bd_oem@takarabio.com to discuss your needs, or visit our OEM page to submit an inquiry.